TY - JOUR AU - Karim, Mohamed Abdel AU - Ibrahim, M , AU - Mohamed,S., AU - Ayda,Y, PY - 2019/08/30 Y2 - 2024/03/29 TI - Isolation , Partial Characterization of a Flavone From Sudanese Terminalia brownii (Comretaceae) Root and Biological Activity of Ethanol Extract JF - IJRDO - JOURNAL OF BIOLOGICAL SCIENCE JA - bs VL - 5 IS - 8 SE - Articles DO - 10.53555/bs.v5i8.3179 UR - https://ijrdo.org/index.php/bs/article/view/3179 SP - 01-08 AB - Terminalia brownii is widely used in African system of medicine as a natural remedy for cough, tonsillitis, typhoid, tooth-ache, snake bite and rheumatic pain . Phytochemical screening of Terminalia brownii root revealed the presence of flavonoids , alkaloids,steroids, tannins, terpenes, saponins and coumarins. A flavonoid - compound I- was isolated from the ethanol extract by  paper chromatography and its structure was partially characterized via some spectral data ( UV and 1HNMR).In the agar diffusion bioassay,the ethanol extract showed significant activity against Pseudomonas aeruginosa and Staphylococcus aureus. It  exhibited moderate activity against Escherichia coli and the yeast Candida albicans . It also showed moderate free radical scavenging capacity  against stable DPPH radicals. ER -