Constituents and Biological Activity of Sudanese Tephrosia apollina (Fabaceae) Seed Oil
Abstract
Tephrosia is a genus in the family Fabaceae. This genus is distributed in tropical and sub-tropical regions.Tephrosia genus manifested a range of biological activities including: antifungal, antiplasmodial, antiinflammatory, antiulcer , antidiabetic and anticancer activities. In this study GC-MS analysis of Tephrosia apollina oil revealed the presence of the following major constituents: i)9-octadecenoic acid methyl ester(31.79%); (ii)9,12-octadecadienoic acid methyl ester(21.34%). ;(iii) hexadecanoic acid methyl ester(17.86%) and (iv)methyl stearate(16.07%).The oil was evaluated for antimicrobial potential. The studied oil showed significant activity against Bacillus subtilis , Staphylococcus aureus and Escherichia coli .It exhibited moderate activity against other test organisms.
Downloads
References
-Muazu J., Kaita A.H. , A review of traditional plants used in the treatment of epilepsy amongst the Hausa/Fulani tribes of northern Nigeria, Afr J Tradit Complement Altern Med, 2008; 5(4):387–90
-Roger J.P., Brian S.M., Anti-epileptic drug. In: Katzung BG (ed.). Basic and clinical pharmacology. Prentice, Hall International (UK) Ltd, London, UK, pp 331–42, 1996.
-Al-Ghamdi F.A., Morphological Diversity of Some Tephrosia Species (Fabaceae) in Saudi Arabia, Am J Plant Sci, 2013; 4(3):543–48
-Chen Y., Yan T., Gao C., Cao W., Huang R., Natural products from the genus Tephrosia, Molecules, 2014; 19(2):1432–58.
-Atilaw Y., Duffy S., Heydenreich M., Muiva-Mutisya L., Avery V.M., Erdelyi M., Yenesew A., Three Chalconoids and a Pterocarpene from the Roots of Tephrosia aequilata, Molecules, 2017; 22(2):E318.
-Ahmed Hassan L.E., Khadeer Ahamed M.B., Abdul Majid A.S., Iqbal M.A., Al Suede F.S., Haque R.A., Ismail Z., Ein O.C., Majid A.M., Crystal structure elucidation and anti-cancer studies of (-)-pseudosemiglabrin: a flavanone isolated from the aerial parts of Tephrosia apollinea. PLoS One, 2014; 9(3):e90806
-Touqeer S., Saeed M.A., Ajaib M., A review on the phytochemistry and pharmacology of genus Tephrosia, Phytopharmacology, 2013; 4(3):598–637.
- Ingham J.L., Markham K.R., Tephrocarpin, a pterocarpan phytoalexin from Tephrosia bidwilli and a structure proposal for acanthocarpan, Phytochemistry, 1980; 21(12):2969–72.
-Babayemi J., Bamikole M.. Supplementary value of Tephrosia bracteolata, Tephrosia candida, Leucaena leucocephala and Gliricidia sepium hay for West African dwarf goats kept on range, J Cent Eur Agric, 2006; 7(2):323–8.
- Ganapaty S., Lakshminarayana K., Lakshmi P., Thomas P.S., Antiprotozoal and cytotoxicity assays of the isolates of Tephrosia tinctoria, Asian J Chem, 2009; 21(2):1007–10.
- Hegazy M.E., El-Hamad H., Mohamed A., El-Halawany A.M., Djemgou P.C., Shahat A.A., Pare P.W., Estrogenic activity of chemical constituents from Tephrosia candida, J Nat Prod, 2011; 74(5):937–42.
-Gomez-Garibay F., Calderón J.S., Quijano L., Domínguez M., Ríos T. ,Viridiflorin, an isoflavone from Tephrosia viridiflora, Phytochemistry, 1985; 24(5):1126–8.
-Stevenson P.C., Kite G.C., Lewis G.P., Forest F., Nyirenda S.P., Belmain S.R., Sileshi G.W., Veitch N.C., Distinct chemotypes of Tephrosia vogelii and implications for their use in pest control and soil enrichment, Phytochemistry, 2012; 78:135–46.
-Chen Y., Yan T., Gao C., Cao W., Huang R., Natural products from the genus Tephrosia, Molecules, 2014; 19(2):1432–58.
-Gora R.H., Baxla S.L., Kerketta P., Patnaik S., Roy B.K., Hepatoprotective activity of Tephrosia purpurea against arsenic induced toxicity in rats, Indian J Pharmacol, 2014; 46(2):197–200.
-Verma N., Neeraj Singh J. , Evaluation of hepatoprotective activity of Tephrosia purpurea Linn. stem, IEJSRJ, 2017; 2(7):1–6
-Praveena R., Amarnath S., Jegadeesan M., Anti-inflammatory activity of Tephrosia purpurea. Root, IJPPR, 2011; 3(4):93–4.
-Ramesh C., Rani P.A., In vivo and in vitro evaluation of Tephrosia calophylla for anti-diabetic properties , Int J Pham Pharm Sci, 2018; 10(6):138–4419
- Arriaga A.M., Malcher G.T.., Lima J.Q, Magalhaes F.E., Gomes T.M., Da Conceicao M., Oliveira F., Andrade-Neto M., Mafezolli J., Santiago G.M., Composition and larvicidal activity of the essential oil from Tephrosia cinerea Pers, JEOR, 2008; 20(5):450–1.
- Luo Z.P., Lin H.Y., Ding W.B., He H.L., Li Y.Z. , Phylogenetic diversity and anti-fungal activity of endophytic fungi associated with Tephrosia purpurea, Mycobiology, 2015; 43(4):435–43.
- Gulecha V., Sivakuma T. , Anti-cancer activity of Tephrosia purpurea and Ficus religiosa using MCF 7 cell lines, Asian Pac J Trop Med, 2011; 4(7):526–9
Copyright (c) 2019 IJRDO - Journal of Biological Science (ISSN: 2455-7676)
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Author(s) and co-author(s) jointly and severally represent and warrant that the Article is original with the author(s) and does not infringe any copyright or violate any other right of any third parties, and that the Article has not been published elsewhere. Author(s) agree to the terms that the IJRDO Journal will have the full right to remove the published article on any misconduct found in the published article.
