Vol 5 No 5 (2019): IJRDO - Journal Of Biological Science | ISSN: 2455-7676
Articles

Isolation and Partial Characterization of Flavone from Sudanese Acacia nilotica subsp. adstringens Pods and Antibacterial activity of Pod Fractions

Mohamed,A.M.
El Sheikh Abdallah Albadry University
Bio
Mayada,I.S.
Sudan University of Science and Technology
Bio
Weam.A.K.
Omdurman Islamic University,
Bio
Published May 17, 2019
Keywords
  • Acacia nilotica subsp. adstringens,
  • Flavonoid,
  • Isolation,
  • Antimicrobial Activity
How to Cite
, M., Mayada,I.S., & Weam.A.K. (2019). Isolation and Partial Characterization of Flavone from Sudanese Acacia nilotica subsp. adstringens Pods and Antibacterial activity of Pod Fractions. IJRDO - Journal of Biological Science (ISSN: 2455-7676), 5(5), 01-09. Retrieved from https://ijrdo.org/index.php/bs/article/view/2870

Abstract

The methanolic extract of  Acacia nilotica subsp. adstringens pods was fractionated over silica gel plates to give a flavonoid-compound I . The structure of compound I was partially characterized via some spectral data:  UV, 1HNMR . Different fractions of acacia nilotica were assessed  for their antimicrobial activity against Gram negative (Escherichia coli and Pseudomonas aeruginos) , Gram positive (Bacillus subtilis and Staphylococcus aureus) and the yeast Candida albicans. The n-butanol and ethanol fractions showed moderate activity against Pseudomonas aeruginosa.The ethyl acetate fraction exhibited moderate activity against Bacillus subtiles while the chloroform fraction showed moderate activity against Bacillus subtilis and Staphylococcus aureus.

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