Isolation and Partial Characterization of Flavone from Sudanese Acacia nilotica subsp. adstringens Pods and Antibacterial activity of Pod Fractions
Abstract
The methanolic extract of Acacia nilotica subsp. adstringens pods was fractionated over silica gel plates to give a flavonoid-compound I . The structure of compound I was partially characterized via some spectral data: UV, 1HNMR . Different fractions of acacia nilotica were assessed for their antimicrobial activity against Gram negative (Escherichia coli and Pseudomonas aeruginos) , Gram positive (Bacillus subtilis and Staphylococcus aureus) and the yeast Candida albicans. The n-butanol and ethanol fractions showed moderate activity against Pseudomonas aeruginosa.The ethyl acetate fraction exhibited moderate activity against Bacillus subtiles while the chloroform fraction showed moderate activity against Bacillus subtilis and Staphylococcus aureus.
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References
- Pengely,A. “Constituents of Medicinal Plants”,2004, CABI Publishing, Wallingford UK.
- Ilić, S.B., Konstantinovic, S.S., Todorović, Z.B., physics chemistry and tenchnology,2004, 3, 67.
-Grotewold, E., “The Science of Flavonoids”,2006, Kluwer Academic Pub., New York.
-Middleton, E.J.C., Kandaswami, T.C. Eur.J.Biochem., 2000, 176, 661 (2000).
- Anderson, J., Anthony, M.S., Public Health Nutr1999, 2, 489 .
-Procházková D, Bousová I, Wilhelmová N.. Fitoterapia. 2011,82(4),513-23.
-Maleśev D, Kunti V.. J Serb Chem Soc. 2007,72(10),921-39.
-Bubols GB, Vianna Dda R, Medina-Remon A, von Poser G, Lamuela-Raventos RM, Eifler-Lima VL,. Mini Rev Med Chem. 2013,13(3),318-34.
-Amić D, Davidović-Amić D, Beslo D, Rastija V, Lucić B, Trinajstić N.. Curr Med Chem. 2007, 14(7),827-45.
-Dugas AJ Jr, Castañeda-Acosta J, Bonin GC, Price KL, Fischer NH, Winston GW.. J Nat Prod. 2000,63(3),327-31.
-Santos MR, Mira L.. Free Radic Res. 2004 Sep,38(9),1011-8.
-Moalin M, van Strijdonck GPF, Beckers M, Hagemen GJ, Borm PJ, Bast A, Molecules. 2011,16(11),9636-50.
-Celik H, Arinç E.. J Pharm Pharm Sci. 2010,13(2),231-41.
-Heijnen CG, Haenen GR, van Acker FA, van der Vijgh WJ, Bast Toxicol in Vitro. 2001,15(1),3-6.
-15- Zechemeister, L., “Progress in the Chemistry of Organic Natural products”,1957, Springer-Verlag, New York, p.17-19 .
-Wright, C.W., Phllipson, J. D., Phytotheraphy Research, 4, 129 (1998).
- Hostettman, k., Marston, A., Maillard, M., Hamberger, M., “Phytochemistry of Plants used in Traditional Medicine”,1995, Oxford Science, Publications, p. 271 .
-Harbrone, J.B., “The Flavonoids”, 1988,Chapman and Hall Ltd, London .
-Ferguson, W.S., Ashworth, D.E.B., Terry, R.A., Nature, 1950, London, 113, 166 .
-Kuhn, R., Moewus, F., Loew, I., Ber. Disch. Chem. Ges,1994, 77, 219 .
-Barnes, R., Harris, S.A., “African Acacias - monographs and Manuals Final Technical Report”,,2002, Oxford Forestry Institute, University of Oxford, p. 21- 26 .
-Mann, A., Gbate, M., Umar, A., “Medicinal and Economic Plants”.2003, Jube Evans Books and Publication, Bide, Nigeria, p. 10 .
-Umalkar, C.V., Begum, S., Nehemiah, K.M.A., Indian phytopath, 1977,29, 469
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