Isolation and Partial Characterization of Flavone from Sudanese Acacia nilotica subsp. adstringens Pods and Antibacterial activity of Pod Fractions

  • Mohamed,A.M. El Sheikh Abdallah Albadry University
  • Mayada,I.S. Sudan University of Science and Technology
  • Weam.A.K. Omdurman Islamic University,
Keywords: Acacia nilotica subsp. adstringens, Flavonoid, Isolation, Antimicrobial Activity


The methanolic extract of  Acacia nilotica subsp. adstringens pods was fractionated over silica gel plates to give a flavonoid-compound I . The structure of compound I was partially characterized via some spectral data:  UV, 1HNMR . Different fractions of acacia nilotica were assessed  for their antimicrobial activity against Gram negative (Escherichia coli and Pseudomonas aeruginos) , Gram positive (Bacillus subtilis and Staphylococcus aureus) and the yeast Candida albicans. The n-butanol and ethanol fractions showed moderate activity against Pseudomonas aeruginosa.The ethyl acetate fraction exhibited moderate activity against Bacillus subtiles while the chloroform fraction showed moderate activity against Bacillus subtilis and Staphylococcus aureus.


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Author Biographies

Mohamed,A.M. , El Sheikh Abdallah Albadry University

El Sheikh Abdallah Albadry University,Faculty of Pharmacy(Sudan)

Mayada,I.S., Sudan University of Science and Technology

Sudan University of Science and Technology, Faculty of Science(Sudan).

Weam.A.K., Omdurman Islamic University,

Omdurman Islamic University, Faculty of Pharmacy(Sudan).


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How to Cite
, M., Mayada,I.S., & Weam.A.K. (2019). Isolation and Partial Characterization of Flavone from Sudanese Acacia nilotica subsp. adstringens Pods and Antibacterial activity of Pod Fractions. IJRDO - Journal of Biological Science (ISSN: 2455-7676), 5(5), 01-09. Retrieved from