Relationship between body weight and blood biochemical measurements resulted from sniffing lead-containing substances of homeless adolescent in Khartoum City, Sudan

  • Leila M. A. Hamed Department of Medical Laboratories, College of Applied Medical Science, Shaqra University, Kingdom of Saudi Arabia
  • Gaafar K. Nogod Central Laboratory of Research and Analysis for Drinking Water, Khartoum, Sudan
  • Hythem S.A. Saeed Dept. of Biochemistry, Faculty of Dental Medicine and Surgery, National University, Sudan
  • Abdelmonem M. Abdellah Allahawi for Research Consultation (ARC), Khartoum North, Sudan
Keywords: biochemical, sniffers, exposure, albumin, bilirubin, cholesterol, triglyceride

Abstract

Sniffing lead-containing substances phenomenon is associated with possible brain damage and severe breathing problems. In this study, a total of 120 sniffers and 40 normal children as control were randomly selected to investigate the effect of sniffing lead-containing substances on the biochemical parameters: Lead (mg/dl), calcium (mg/dl), total protein (mg/dl), albumin (mg/dl), total bilirubin (mg/dl), direct bilirubin (mg/dl), indirect bilirubin (mg/dl), AST (U/L), ALT (U/L), cholesterol and triglyceride. Result indicated that all of the studied biochemical parameters were not significantly affected by age of sniffers, but some parameters such as lead, total bilirubin and indirect bilirubin were slightly increased with the increase of sniffers age. Accordingly, long-term of sniffing lead-containing substances causes negative influence on children’s intelligence and behavioral development.

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References

Abdalla FAB, Saeed HAS, Abbas AA and Abdellah AM (2017). Lead poisoning from cars exhausts among primary school children in Sudan. Asian Journal of Science and Technology, 08(10): 5970-5973.

Ali ZH (2007). The effect sniffing lead on blood of adolescent’s homeless ainls gasoline sniffers in Bashair camp Khartoum. Sudan. Master of Science in biochemistry. Omdurman Islamic University.

ATSDR (Agency for Toxic Substances and Disease Registry). (2007). Toxicological profile for Lead. Atlanta, GA: U.S. Department of Health and Human Services, Public Health Service.

Bellinger DC, Stiles KM.and Needleman HL (1992). Low-level lead exposure, intelligence and academic achievement: A long-term follow-up study. Pediatrics 90:855-861.

Bhattacharya A, Shukla R, Bornschein R, et al. (1988). Postural disequilibrium quantification in children with chronic lead exposure: A pilot study. Neurotoxicology 9:327-340.

Bornschein RL, Succop PA and Krafft KM (1986). Exterior surface dust lead, interior house dust lead and childhood lead exposure in an urban environment. In: Hemphil DD, ed. Trace substances in environmental health. Vol. 20. Columbia, MO: University of Missouri 322-332.

Brady M (1992). Heavy Metal. Canberra:Aboriginal studies press, AIATSIS.

Brady M and Torzillo P (1995). Petrol sniffing down the track. Medical Journal of Australia, 160(21), 176–177.

Burns C (1996). An End of Petrol Sniffing. Ph D thesis, Sydney University.

Butrimovitz 1GP and Pudy WC (1997). (1977). The determination of lead in by Atomic Absorption Spectrometry. Ann. Chim. Blood plasma Acta 94.63 Pb (30).

Cannon DC, Olifzky I and Inkpen JA (1974). Protein. Cli – chem. Principle and technics,zed. Cannon and winkelman editors. New York, PP. 407 – 421.

Cava RJ, Hor YS. Cava RJ (2011). Pressure Stabilized Se-Se Dimer Formation in PbSe2". Solid State Sciences13: 38–41. Bibcode:2011SSSci..13.38B.doi:10.1016/j.solidstatesciences.2010.10.003.

Cheesbrough M (2006). District laboratory practice in tropical countries, part 1, 2rd addition, Cambridge University press, New York – USA, 350, 404

Chen A, Dietrich KN, Ware JH, et al. (2005). IQ and blood lead from 2 to 7 years of age: Are the effects in older children the residual of high blood lead concentrations in 2-year-olds? Environ Health Perspect 113(5):597-601.

Davis JM and Svendsgaard DJ (1987). Lead and child development. Nature 329:297-300.

Doumas BT, Waston WA and Bigg hG, (1971). Albumin standard and the measurement of serum albumin with bromocresol green. Cli- chem. U.S. 31, 87 – 96.

Ferguson A, Bursac Z, Kern DF. Arkansas (2011). People Participating in Lead Education (APPLE): results of a Lead-safe training program. J Community Health; 36(3):367–374.

Hamed LMA, Nogod GK, Saeed HSA, Abdalla FAB, Abdellah AM and Abbas AA (2021a). The Effect of Addiction to Sniffing Lead-containing Substances on Blood Biochemical Measurements of Homeless Adolescents in Khartoum City, Sudan, Greener Journal of Environmental Management and Public Safety, 10(1): 1-9.

Hamed LMA, Nogod GK, Saeed HSA, and Abdellah AM. (2021b). Correlation between age and blood biochemical changes of homeless adolescent resulted of sniffing lead-containing substances, International Journal of Green and Herbal Chemistry, 10(1): 015-025.

Hodge AT (1992). Roman Aqueducts & Water Supply. London: Duckworth. ISBN 0-7156-2194-7.

Hou Y, Burkhard B and Müller F (2013). Uncertainties in landscape analysis and ecosystem service assessment. Journal of Environmental Management 127, S117–S131

Kosnett M.J. (2006). "Lead". In Olson, K.R. Poisoning and Drug Overdose (5th ed.). McGraw-Hill Professional. p. ISBN 0-07-144333-9.

Mohammed Ali SA (2007). Determination of lead in Air and Blood Samples from People in Khartoum State-master of science in biochemistry. Omdurman Islamic University.

Mosey A (1997). Report on petrol-sniffing in central Australia alcohol and other drugs program. Alice Springs: Territory Health services, unpublished report.

Mushak P and Carocetti AH (1989). Determination of numbers of lead –exposed American children as function of lead source. Integrated summery of a report to U.S. congress on childhood lead poisoning. Sources of U.S. child lead exposure, 210-229.

Needleman HL, Schell A and Bellinger D (1990). The long-term effects of exposure to low doses of lead in childhood. An 11-year follow-up report. N Engl J Med 322:83-88.

Polyanskiy NG, Fillipova NA (1986). ed. Аналитическая химия элементов: Свинец [Analytical Chemistry of the Elements: Lead] (in Russian). Nauka.

Reitman S and Frankel M (1957). Acolorimetric method for the determination of serum glutamate oxaloacetatic acid and pyruvic acid transaminases American of Clin-Pathol., 28: 56 – 63.

Rogan WJ, Dietrich KN, Ware JH (2001). The effect of chelation therapy with succimer on neuropsychological development in children exposed to lead. N Engl J Med 344(19):1421-1426.

Saeed HSA, Abdellah AM, Abdalla FAB and Abbas AA (2017). Effect of air lead pollution on blood bilirubin and lactate dehydrogenase levels among occupationally exposed workers in main Sudanese cities. IOSR Journal of Applied Chemistry (IOSR-JAC) 10(1): 47-52

Schutz A, Skerfving S and Ranstam J (1987). Kinetics of lead in blood after the end of occupational exposure. Scand J Work Environ Health 13:221-231.

Shukla R, Bornschein RL, Dietrich KN (1989). Fetal and infant lead exposure: Effects on growth in stature. Pediatrics 84:604-612.

Published
2021-11-30
How to Cite
Hamed, L. M. A., Nogod, G. K., Saeed, H. S., & Abdellah, A. M. (2021). Relationship between body weight and blood biochemical measurements resulted from sniffing lead-containing substances of homeless adolescent in Khartoum City, Sudan. IJRDO - Journal of Agriculture and Research (ISSN: 2455-7668), 7(11), 01-08. Retrieved from https://ijrdo.org/index.php/ar/article/view/4203