Correlation of Salivary Glucose with Serum Glucose in Diabetic Patients
Abstract
Background and aim: Composition of Saliva which has similarity with serum has diagnostic value for different diseases. Recently, studying salivary glucose is the major issue for diagnosing Diabetes mellitus. The aim of this study was to determine association between salivary and serum glucose in Diabetes mellitus.
Material and Method: This cross sectional study was conducted on 384 diabetic patients who were registered for fasting serum glucose detection in laboratory of IBNE-SENA EMERGENCY HOSPITAL. In this study 269 were female and 115 were male. Glucose in serum and saliva was determined by Glucose oxidase-peroxidase method by semiautomatic analyzer. For detecting association bivariate correlation and linear regression was performed.
Results: In this study mean age was 50±0.6 years, Mean fasting salivary glucose and mean fasting serum glucose were 28.19±0.3 and 149.39±3.04mg/dl respectively. Totally 56.3% of samples had serum glucose equal and higher than 126mg/dl. Difference of mean salivary glucose according to age and gender were not significant. In 56.3 % of samples salivary glucose had association with serum glucose but this association was just significant when serum glucose was equal to 126mg/dl or more than it.
Conclusion: Fasting Serum glucose more than threshold indicate positive correlation with fasting salivary glucose and according to linear correlation that was found serum glucose could be predictable when fasting salivary glucose was determined but there was no correlation with gender and age.
Downloads
References
2-Arati S. Panchbhai, Shirish S. Degwekar and Rahul R. Bhowte. Estimation of salivary glucose, salivary amylase, salivary total protein and salivary flow rate in diabetics in India, Journal of Oral Science2010; 52(6):359-368.
3- Agrawal RP, Sharma N, Rathore MS, Gupta VB, Jain S, Agarwal V and Goyal S. Noninvasive Method for Glucose Level Estimation by Saliva, J Diabetes Metab 2013, 4:5.
4- Dipti KH, Maitreyee DS, Shivashankara AR, Avinash SS, Malathi M. A correlative study of salivary and plasma glucose levels in type 2 diabetic patients with and without complications. International Journal of Clinical Biochemistry and Research 2016; 3(2):250-254.
5- Preethi Balan , Subhas G. Babu , Kumari N. Sucheta, Shishir R. Shetty, Anusha L. Rangare , Renita L.Castelino , Areekat K. Fazil. Can saliva offer an advantage in monitoring of diabetes mellitus?– A case control study. J Clin Exp Dent. 2014;6(4):e335-8.
6- Panda Abikshyeet, Venkatapathy Ramesh, Nirima Oza. Glucose estimation in the salivary secretion of diabetes mellitus patients, Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2012; 5:149–154
7- Bhumika J Patel, Bela Dave, Dilip Dave, Payel Karmakar , Mona Shah, Bhumi Sarvaiya. Comparison and Correlation of Glucose Levels in Serum and Saliva of both Diabetic and Non-diabetic Patients, Journal of International Oral Health 2015; 7(8):70-76.
8- J Max Goodson. Salivary Glucose: A Metabolic Disease Marker And a Risk Factor for Oral Disease Development, Adv Dent & Oral Health 2017; 4(3):ID.555640.
9- Amit Ladgotra, Pradhuman Verma, SEETHARAMAIAHSUNDERRAJ. Estimation of Salivary and Serum Biomarkers in Diabetic and Non Diabetic Patients - A Comparative Study, Journal of Clinical and Diagnostic Research 2016 Jun; 10(6): ZC56-ZC61.
10- Seyyed Omid Mahdavi, Sedighe Hashemi, Najmeh Sadat Boostani, Haleh Zokaee. A New Method to Evaluate Fasting Plasma Glucose by Salivary Glucose Measurement, Iranian Journal of Diabetes and Obesity 2012; 4(3).
11- Avandindra Kumar, Muesh Kumar, ViabhavKamal, Sourman Mandal, Kamna Gorka, Avanish Kumar, Evualtion of Salivary and serum glucose levels in Diabetes mellitus : A comparative study, International journal of oral care research 2016; 4(1):39-44.
Copyright (c) 2018 IJRDO - Journal of Health Sciences and Nursing (ISSN: 2456-298X)
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Author(s) and co-author(s) jointly and severally represent and warrant that the Article is original with the author(s) and does not infringe any copyright or violate any other right of any third parties, and that the Article has not been published elsewhere. Author(s) agree to the terms that the IJRDO Journal will have the full right to remove the published article on any misconduct found in the published article.
